ABCs Series Education Fact Sheets

ABCs of: Acute Limb Ischemia

Acute limb ischemia (ALI) refers to the sudden decrease in limb perfusion that threatens limb viability.

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  1. Creager, M. A., Kaufman, J. A., & Conte, M. S. (2012). Clinical practice. Acute limb ischemia. The New England journal of medicine, 366(23), 2198–2206.  
  2. Howard, D. P., Banerjee, A., Fairhead, J. F., Hands, L., Silver, L. E., Rothwell, P. M., & Oxford Vascular Study (2015). Population-Based Study of Incidence, Risk Factors, Outcome, and Prognosis of Ischemic Peripheral Arterial Events: Implications for Prevention. Circulation, 132(19), 1805–1815.
  3. Results of a prospective randomized trial evaluating surgery versus thrombolysis for ischemia of the lower extremity. The STILE trial. (1994). Annals of surgery, 220(3), 251–268. 
  4. Nilsson, L., Albrechtsson, U., Jonung, T., Ribbe, E., Thorvinger, B., Thörne, J., Astedt, B., & Norgren, L. (1992). Surgical treatment versus thrombolysis in acute arterial occlusion: a randomised controlled study. European journal of vascular surgery, 6(2), 189–193. 
  5. Natarajan, B., Patel, P., & Mukherjee, A. (2020). Acute Lower Limb Ischemia-Etiology, Pathology, and Management. The International journal of angiology : official publication of the International College of Angiology, Inc, 29(3), 168–174.


Content – Eva Teo; Design – Hoo Zhi Ai (SIGMUM Committee of 2022/2023)



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