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ABCs of: Necrotising Fasciitis

Necrotising fasciitis is a rare but serious bacterial infection that affects the tissue beneath the skin and surrounding muscles and organs.

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FACT SHEET

References

  1. Bonne, S. L., & Kadri, S. S. (2017). Evaluation and Management of Necrotizing Soft Tissue Infections. Infectious disease clinics of North America, 31(3), 497–511. https://doi.org/10.1016/j.idc.2017.05.011 
  2. Davoudian, P., & Flint, N. J. (2012). Necrotizing fasciitis. Continuing Education in Anaesthesia Critical Care & Pain, 12(5), 245-250. doi:10.1093/bjaceaccp/mks033
  3. Drake, D. B., Woods, J. A., Bill, T. J., Kesser, B. W., Wenger, M. A., Neal, J. G., & Edlich, R. F. (1998). Magnetic Resonance Imaging in the Early Diagnosis of Group A β Streptococcal Necrotizing Fasciitis: A Case Report 11Clinical Communications (Adults) is coordinated by Ron M. Walls, MD, of Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts. The Journal of Emergency Medicine, 16(3), 403-407. doi:https://doi.org/10.1016/S0736-4679(98)00013-4 
  4. El-Menyar, A., Asim, M., Mudali, I. N., Mekkodathil, A., Latifi, R., & Al-Thani, H. (2017). The laboratory risk indicator for necrotizing fasciitis (LRINEC) scoring: the diagnostic and potential prognostic role. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 25(1), 28. https://doi:10.1186/s13049-017-0359-z 
  5. Erichsen Andersson, A., Egerod, I., Knudsen, V. E., & Fagerdahl, A. M. (2018). Signs, symptoms and diagnosis of necrotizing fasciitis experienced by survivors and family: a qualitative Nordic multi-center study. BMC infectious diseases, 18(1), 429. https://doi.org/10.1186/s12879-018-3355-7 
  6. Fernando, S. M., Tran, A., Cheng, W., Rochwerg, B., Kyeremanteng, K., Seely, A., Inaba, K., & Perry, J. J. (2019). Necrotizing Soft Tissue Infection: Diagnostic Accuracy of Physical Examination, Imaging, and LRINEC Score: A Systematic Review and Meta-Analysis. Annals of surgery, 269(1), 58–65. https://doi.org/10.1097/SLA.0000000000002774  
  7. Korhonen K. (2000). Hyperbaric oxygen therapy in acute necrotizing infections. With a special reference to the effects on tissue gas tensions. Annales chirurgiae et gynaecologiae, 89 Suppl 214, 7–36.
  8. Misiakos, E. P., Bagias, G., Patapis, P., Sotiropoulos, D., Kanavidis, P., & Machairas, A. (2014). Current Concepts in the Management of Necrotizing Fasciitis. Frontiers in Surgery, 1. doi:10.3389/fsurg.2014.00036  
  9. Stevens, D. L., & Bryant, A. E. (2017). Necrotizing Soft-Tissue Infections. The New England journal of medicine, 377(23), 2253–2265. https://doi.org/10.1056/NEJMra1600673

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